Genetic Variability of Plasmodium malariae dihydropteroate synthase (dhps) in Four Asian Countries

TitleGenetic Variability of Plasmodium malariae dihydropteroate synthase (dhps) in Four Asian Countries
Publication TypeJournal Article
Year of Publication2014
AuthorsTanomsing, N, Mayxay, M, Newton, PN, Nosten, F, Dolecek, C, Hien, TT, White, NJ, Day, NP, Dondorp, AM, Imwong, M
JournalPLoS ONE
Volume9
Issue4
Paginatione93942
Date Published2014
ISBN Number1932-6203 (Electronic)1932-6203 (Linking)
Abstract

The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance.

URLhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974843/pdf/pone.0093942.pdf
Short TitlePloS one