Capsular typing method for Streptococcus agalactiae using whole genome sequence data

TitleCapsular typing method for Streptococcus agalactiae using whole genome sequence data
Publication TypeJournal Article
Year of Publication2016
AuthorsSheppard, AE, Vaughan, A, Jones, N, Turner, P, Turner, C, Efstratiou, A, Patel, D, Walker, AS, Berkley, JA, Crook, DW, Seale, AC
JournalJ Clin Microbiol
Date Published03/2016
ISBN Number1098-660X (Electronic)0095-1137 (Linking)
Abstract

Group B streptococcus (GBS) capsular serotype is a major determinant of virulence, and affects potential vaccine coverage. Here we report a whole genome sequencing-based method for GBS serotype assignment. This shows high agreement (kappa=0.92) with conventional methods, and increased serotype assignment (100%) to all ten capsular types.

URLhttp://jcm.asm.org/content/54/5/1388.full.pdf
Short TitleJournal of clinical microbiology