Capsular typing method for Streptococcus agalactiae using whole genome sequence data
Title | Capsular typing method for Streptococcus agalactiae using whole genome sequence data |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Sheppard, AE, Vaughan, A, Jones, N, Turner, P, Turner, C, Efstratiou, A, Patel, D, Walker, AS, Berkley, JA, Crook, DW, Seale, AC |
Journal | J Clin Microbiol |
Date Published | 03/2016 |
ISBN Number | 1098-660X (Electronic)0095-1137 (Linking) |
Abstract | Group B streptococcus (GBS) capsular serotype is a major determinant of virulence, and affects potential vaccine coverage. Here we report a whole genome sequencing-based method for GBS serotype assignment. This shows high agreement (kappa=0.92) with conventional methods, and increased serotype assignment (100%) to all ten capsular types. |
URL | http://jcm.asm.org/content/54/5/1388.full.pdf |
Short Title | Journal of clinical microbiology |